Nicotinamide
Vitamin B3 derivative, studied in cellular energy and the skin’s natural repair pathways.
Read the research ↗: Nicotinamide
Ingredients that have been shown to reduce the impacts of short and long term sun damage
View full Supplement Facts ↗Amounts per daily serving of powder.
Vitamin B3 derivative, studied in cellular energy and the skin’s natural repair pathways.
Read the research ↗: NicotinamideA tropical fern extract studied for enhancing the skin’s response to excess UV exposure.
Read the research ↗: Polypodium leucotomosA moisture-binding molecule studied in oral supplementation and skin hydration.
Read the research ↗: Hyaluronic acidA powerful carotenoid antioxidant with published research on skin longevity, improved skin quality and health.
Read the research ↗: AstaxanthinHydrolyzed bovine peptides. Research explores hydration, elasticity and skin appearance.
Read the research ↗: Collagen peptidesAn essential nutrient involved in normal collagen formation and antioxidant function.
Read the research ↗: Vitamin CAn antioxidant studied in skin appearance and pigmentation research.
Read the research ↗: GlutathioneA compound involved in cellular signaling and skin hydration levels.
Read the research ↗: Inositol
>50%
Observed when supplementation began after a first skin cancer.
20%fewer precancerous lesions at 9 months
JAMA observational cohort; matched comparison.
JAMA observed a 54% lower hazard when nicotinamide began after the first skin cancer. In a separate NEJM trial, actinic keratosis counts were 20% lower at 9 months versus placebo.
JAMA: 33,822 veterans · NEJM: 386 high-risk adults
Breglio et al. · JAMA Dermatology, 2025 ↗ — Nicotinamide Chen et al. · NEJM, 2015 ↗ — Nicotinamide
80%
Measured by colorimetry after a PLE-containing supplement.
Colorimetric response after five days of supplementation.
A PLE-containing supplement improved measured UV response in 80% of participants. A separate 8-week trial of PLE, red orange and vitamins found greater UV tolerance and reduced erythema after exposure.
25 adults completed · PLE-containing supplement · 5 days
Hussain et al. · Arch Dermatol Res, 2025 ↗ — Polypodium leucotomos Keršmanc et al. · Red orange + PLE, 2025 ↗ — Polypodium leucotomos Kohli et al. · JAAD, 2017 ↗ — Polypodium leucotomos
≈11%
Approximate change from published group means.
Oral hyaluronan improved facial hydration. Measured facial water loss also fell ≈16% from baseline.
40 adults · Randomized trial · 12 weeks
Hsu et al. · Nutrients, 2021 ↗ — Hyaluronic acidIngredient studies are not trials of the finished formula. Outcomes depend on the dose, form, population and study protocol.
80%erythema
reduction
In a significant portion of participants, post-ingestion redness was visibly reduced compared to the baseline data.
Controlled broad-spectrum laser calibrated to simulate 6 hours of peak midday sun (UVA + UVB).
One hour post-exposure, measured erythema (redness).
Participants then consumed one dose of Sun Powder and were exposed again to the laser.
One hour post-ingestion, measured erythema again.
Redness is the earliest, most visible sign of UV damage — a proxy for DNA damage, inflammation, and sunburn. Reducing it post-exposure signals faster recovery and protection.
1 hour post-exposure to UVA + UVB
1 hour post-ingestion & more UVA + UVB exposure

Nutrients help sustain normal cellular functions, including energy production and repair.
Antioxidants play a role in the body’s response to everyday oxidative stress.
Collagen and hyaluronic acid are part of skin’s supporting matrix.
No. Keep using sunscreen, protective clothing and shade. Sun Powder is a daily supplement alongside those habits.
Exploratory work can guide larger studies. It is an early signal to investigate, with clear limits on what we can conclude.

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